They add that mixing vaccines can also increase flexibility when doses of one particular vaccine are not readily available.ĭr. The National Institutes of Health says mixing vaccines may enhance immune response. The agency also recommends that some immunocompromised people 12 years and older get a second booster 4 months after their first one. In addition, the Food and Drug Administration says a second booster dose of the Pfizer-BioNTech or the Moderna COVID-19 vaccine can be given to people 50 years of age and older at least 4 months after getting their first booster dose. The Centers for Disease Control and Prevention (CDC) currently recommends COVID-19 vaccine boosters for everyone ages 12 years and older. If you’ve been vaccinated against COVID-19, your protection against the novel coronavirus may decrease over time, especially with the introduction of new variants. They add that there is evidence that getting a booster different from your original inoculations can improve immune response.Some experts say people under the age of 65 who are in good health may not need the extra vaccination at this time, however.Federal officials have approved a second COVID-19 booster shot for people over the age of 50.Share on Pinterest Experts say not everyone necessarily needs a second COVID-19 booster at this moment.